> For the complete documentation index, see [llms.txt](https://docs.nested-knowledge.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://docs.nested-knowledge.com/guides/nested-knowledge-guides.md). # Nested Knowledge Guides Nested Knowledge Guides are designed to assist you in conducting your review within **Nested Knowledge.** Here we provide guidance by review type, what NK tools to use and links to full instructions in our Documentation. We also provide guidance on writing search queries within the databases offered in the NK automatic search function. ### Review Type Guides Each review type carries different expectations for timeline, protocol, and reporting so it is important to start with the right guide. Each covers the NK tools used for each review type. Pair it with the matching [Best Practices](https://docs.nested-knowledge.com/best-practices/) page.


Systematic Literature Review	Set up and run a systematic literature review in Nested Knowledge.	Systematic Literature Review
Meta-analysis	Set up and run a meta-analysis in Nested Knowledge.	Meta-Analysis
Targeted Literature Review	Set up and run a targeted or rapid literature review in Nested Knowledge.	Conduct A Rapid Review
Evaluations for HTA submission	Set up your nest to support an HTA submission.	Evaluations for HTA submission
Gap Analysis	Set up and run a gap analysis in Nested Knowledge.	Gap Analysis
Narrative Review	Set up and run a narrative review in Nested Knowledge.	Narrative Review
Scoping Review	Set up and run a scoping review in Nested Knowledge.	Scoping Review

### Write a Search Query Well-structured search queries make your evidence search transparent and reproducible. Use the guide for your database to learn its supported fields, operators, and syntax.


Write a Search Query - Overview	Learn how to write search queries for the databases that support automatic search.	Overview
PubMed	Learn how to write a PubMed search query.	PubMed
ClinicalTrials.gov	Learn how to write a ClinicalTrials.gov search query.	ClinicalTrials.gov
Embase	Learn how to write an Embase search query.	Embase
OpenAlex	Learn how to write an OpenAlex search query.	OpenAlex
MAUDE	Learn how to write a MAUDE search query.	MAUDE
EuropePMC	Learn how to write a EuropePMC search query.	EuropePMC
DOAJ	Learn how to write a DOAJ search query.	DOAJ

--- # Agent Instructions This documentation is published with GitBook. GitBook is the documentation platform designed so that both humans and AI agents can read, navigate, and reason over technical content effectively. Learn more at gitbook.com. ## Querying This Documentation If you need additional information that is not directly available in this page, you can query the documentation by asking a question. Perform an HTTP GET request on the following URL with the `ask` and `goal` query parameters: ``` GET https://docs.nested-knowledge.com/guides/nested-knowledge-guides.md?ask=&goal= ``` `ask` is the immediate question: it should be specific, self-contained, and written in natural language. `goal` is what the user is ultimately trying to achieve, the reason they need the answer. Sharing it helps GitBook give you a better, more relevant answer. A goal is most helpful when it describes the outcome the user wants rather than restating the question. For example, with `ask=how do I create an API token`, a goal like `automate deployments from our CI pipeline` lets GitBook tailor the answer to that use case. The response will contain a direct answer to the question and relevant excerpts and sources from the documentation. Use this mechanism when the answer is not explicitly present in the current page, you need clarification or additional context, or you want to retrieve related documentation sections.